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When Stanley Kubrick recruited Arthur C. Clarke to collaborate on "the proverbial intelligent science fiction film," it's a safe bet neither the maverick auteur nor the great science fiction writer knew they would virtually redefine the parameters of the cinema experience. A daring experiment in unconventional narrative inspired by Clarke's short story "The Sentinel," 2001: A Space Odyssey is a visual tone poem (barely 40 minutes of dialogue in a 139-minute film) that charts a phenomenal history of human evolution.

Sean Penn and Benecio Del Toro, two of the most gripping actors around, play wildly different men linked through a grieving woman (Naomi Watts, Mulholland Drive, The Ring) in 21 Grams. Del Toro (Traffic, The Usual Suspects) delves deep into the role of an ex-con turned born-again Christian, a deeply conflicted man struggling to set right a terrible accident, even at the expense of his family. Penn (Mystic River, Dead Man Walking) captures a cynical, philandering professor in dire need of a heart transplant, which he gets from the death of Watts' husband.

In this hilarious farce, three of Hollywood's favorite female stars - Jane Fonda, Lily Tomlin and Dolly Parton - live every secretary's dream as they turn the tables on their boss and turn their male controlled workplace into a model office. At Consolidated, the office manager (Tomlin), the vice president's secretary (Parton) and the newest employee (Fonda) become great friends as they share their resentment about their egotistical, sexist boss (Dabney Coleman).

The quintessential movie spoof that spawned an entire genre of parody films, the original Airplane! still holds up as one of the brightest comedic gems of the '80s, not to mention of cinema itself (it ranked in the top 5 of Entertainment Weekly's list of the 100 funniest movies ever made). The humor may be low and obvious at times, but the jokes keep coming at a rapid-fire clip and its targets--primarily the lesser lights of '70s cinema, from disco films to star-studded disaster epics--are more than worthy for send-up.

Twisty brilliance from screenwriter Charlie Kaufman and director Spike Jonze, the team who created Being John Malkovich. Nicolas Cage returns to form with a funny, sad, and sneaky performance as Charlie Kaufman, a self-loathing screenwriter who has been hired to adapt Susan Orlean's book The Orchid Thief into a screenplay.

In the Watergate Building, lights go on and four burglars are caught in the act. That night triggered revelations that drove a U.S. President from office. Washington reporters Bob Woodward (Robert Redford) and Carl Bernstein (Dustin Hoffman) grabbed the story and stayed with it through doubts, denials, discouragement. All The President's Men is their story. Directed by Alan J. Pakula and based on the Woodward/Bernstein book, the film won four 1976 Academy Awards: Best Supporting Actor/Jason Robards, Adaptation Screenplay, Art Direction and Sound.

The 1982 sequel to Airplane! is basically more of the same class-clown ironies but with a more forced feeling to the jokes. In the first film, veterans such as Peter Graves, Robert Stack, and Lloyd Bridges were feeling their way through self-parody, and the air of experimentation was part of the fun. By this film, however, everybody knows what's up, and the assuredness of new cast members Raymond Burr, William Shatner, and Chuck Connors is almost counterproductive. Still, there's lots to laugh about.

You know that old dramatic principle of suspension of disbelief? You'll have to rely on it for this box-office smash, but you won't be disappointed. Harrison Ford plays a U.S. president who single-handedly employs his rigid antiterrorism policy when a band of Russian thugs hatch a mid-flight takeover of Air Force One. Gary Oldman, who chews the scenery as the lead terrorist, will shoot a hostage at the slightest provocation. Glenn Close plays the sternly pragmatic vice president who negotiates with Oldman from her Washington seat of power.

Rob Lowe doesn't want to get serious. Demi Moore doesn't want to get used. Together, they're an unforgettable couple in the sexy contemporary comedy, About Last Night... After drinks at a favorite Chicago hang-out, Danny Martin (Lowe) and Debbie Sullivan (Moore) head to Danny's place to indulge in the predictable singles quest - the one-night stand. Their affair is casual, sensual and supposedly over until something surprising happens. They want to see each other again.

Set in New York City in 1961, 61* is a film directed by Billy Crystal for baseball lovers. Zooming in on Yankee players Roger Maris and Mickey Mantle, the film follows these two opposites as they attempt to break Babe Ruth's 1927 home run record. In heated competition, the two players each try to score over 60 home runs and set the new world record. While the fans align themselves with one player to be the winner, the players choose the other, igniting the playing field with tension, excitement, and anticipation.